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Helping Americans Get The Truth About Prescription Drug Savings
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People’s Pharmacy Talks About Huge Savings on Narrow Therapeutic Index Drugs from Canada

People's Pharmacy on NTI Drug Savings in Canada

People’s Pharmacy on NTI Drug Savings in Canada

This past summer we wrote about The Graedon’s Guide to Saving Money on Medicine, by the People’s Pharmacy, as a very worthwhile read. One of its sections talked about Narrow Therapeutic Index drugs for which generics are usually low cost and available in the U.S. but for some patients only the brand works: and the brands are very expensive. NTI drugs are those for which the precision of a medication’s dosage is of even greater importance than for most medications. Often these drugs are measured in micrograms not milligrams.

In its Guide, the People’s Pharmacy mentioned several popular medications that fall into the NTI category. We researched their prices and found medications on which Canadian online pharmacies offer spectacular savings, often 80%. They wrote about some of our findings in an article this week called: Can you trust Canadian online pharmacies?

As we’ve written before, many Canadian online pharmacies are really international online pharmacies because for years they’ve been partnering with pharmacies in other countries not just filling orders from Canada. But what was interesting about our data on the NTI drugs is that most of the lowest prices were in fact in Canada, not international pharmacies elsewhere.

Expect more in the New Year on how to get to the brand name drug you want at a price you can afford – including a deeper discussion on Narrow Therapeutic Index Drugs.

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Is Synthroid in Canada the same as in the U.S.?

synthroid-postSynthroid is the brand name for a medication called levothyroxine, which is manufactured by drug company Abbvie in the U.S. and Mylan in Canada. It treats hypothyroidism, as well as enlarged thyroid gland and thyroid cancer. Synthroid sells for about $100 for a three-month supply in the U.S. compared to $32 in Canada. Over the course of a year, since this is a maintenance medication, the annual costs are $400 vs. $128. You compare Synthroid brand prices here. This is a very popular drug: about 23 million prescriptions are written monthly for Synthroid. For Americans who do not have insurance or their insurance doesn’t cover Synthroid, buying it from Canada means real savings. But will they be getting the exact same drug?

After all, there are generic versions of levothyroxine sold in the U.S. that cost even less than Synthroid in Canada: $10 at Walmart for a three-month supply. For most medications (but there are exceptions) your best bet is the lower cost U.S. generic compared to a higher cost brand drug internationally. In the U.S., the FDA affirms that approved generics are bioequivalent to the brands, meaning the active ingredient has the same rate and extent of absorption in the bloodstream (for all intents and purposes they are the same). But for some medications, especially those with a narrow therapeutic index, your provider may not want you to take a generic.  Medications with a narrow therapeutic index have a narrow range between the drug’s risks and its benefits and small differences in dose or blood concentration may matter, meaning it’s more critical that the amount of pharmaceutical ingredient is precise and delivered correctly through the bloodstream. But what about brand products of the same medication made in different countries? (more…)

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